What hormonal alteration is commonly associated with excess androgens during pregnancy?

Excess androgens during pregnancy are closely associated with polycystic ovary syndrome (PCOS). In PCOS, a hormonal imbalance leads to increased production of androgens, which can result in various reproductive and metabolic challenges. During pregnancy, women with a history of PCOS may exhibit elevated androgen levels, which can affect fetal development and lead to complications such as gestational diabetes.

The presence of androgens is typically less pronounced in conditions like hypothyroidism, type 2 diabetes, or hypoparathyroidism. These conditions do not primarily involve the overproduction of androgens and have different underlying mechanisms and hormonal profiles. In contrast, the link between androgens and PCOS illustrates how this hormonal alteration can directly impact pregnancy outcomes and highlight the significance of managing such conditions during gestation.