What is the function of amylin in glucose regulation?

Amylin plays a crucial role in the regulation of glucose homeostasis and is co-secreted with insulin from the beta cells of the pancreas. Its primary function includes slowing gastric emptying, which helps regulate the timing of glucose entering the bloodstream. By doing so, amylin contributes to the prolonged release of glucose into the bloodstream after meals, preventing spikes in blood sugar levels.

Additionally, amylin promotes satiety, enhancing the feeling of fullness after eating. This effect can help reduce overall caloric intake and assist in weight management, which is particularly beneficial for individuals with insulin resistance or diabetes.

In combination, these actions help maintain more stable blood glucose levels, making it a key hormone in glucose regulation. As a result, it plays an essential part in the homeostatic mechanisms that govern how the body processes and responds to food intake.